OrbiSIMS – simultaneous high-mass resolving power and high-spatial resolution mass spectrometry imaging for biological and advanced materials characterisation (Великобритания (Англия, Шотландия, Уэльс) - Тендер #37715936)

Print or Save this Notice Download PDF Download HTML Download XML

Voluntary ex ante transparency notice

Directive 2014/24/EU

Section I: Contracting entity

I.1) Name and addresses

National Physical Laboratory

Hampton Road

Teddington

TW11 0LW

UK

Contact person: Mandy Morgan

Telephone: +44 2089436731

E-mail: mandy.morgan@npl.co.uk

NUTS: UK

Internet address(es)

Main address: www.npl.co.uk

I.4) Type of the contracting authority

Body governed by public law

I.5) Main activity

Other: Research

Section II: Object

II.1) Scope of the procurement

II.1.1) Title

OrbiSIMS – simultaneous high-mass resolving power and high-spatial resolution mass spectrometry imaging for biological and advanced materials characterisation

II.1.2) Main CPV code

38000000

II.1.3) Type of contract

Supplies

II.1.4) Short description

NPL pioneered the next generation OrbiSIMS technology introduced in detail in Nature Methods (2017, PMID: 29131162). The instrument is equipped with a time-of-flight mass spectrometer (ToF) for high-speed imaging of large areas or in 3D. It is also equipped with a high-field Orbitrap mass spectrometer with a mass resolving power of >240,000 at m/z 200 and a mass accuracy of approximately 1 ppm. Both ToF and Orbitrap analysers can be used simultaneously or separately. The OrbiSIMS shall be able to carry out cryogenic analysis under ultra-high vacuum with sample holder temperatures below –150 oC.

II.1.6) Information about lots

This contract is divided into lots: No

II.1.7) Total value of the procurement

Value excluding VAT: 2 254 326.75 EUR

II.2) Description

II.2.3) Place of performance

NUTS code:

UK

II.2.4) Description of the procurement

The OrbiSIMS instrument shall be equipped with a time-of-flight mass spectrometer (ToF) for high-speed imaging of large areas or in 3D. It shall also be equipped with a high-field Orbitrap mass spectrometer with a mass resolving power of >240,000 at m/z 200 and a mass accuracy of ~ 1 ppm. The instrument shall be equipped with 3 primary ion beams which are optimal for different materials systems. (1) A 20 kV gas cluster ion source with a spatial resolution < 2 µm used for biological imaging and depth-profiling of organic materials, (2) a low energy (250 eV to 2000 eV) dual source (Cs and O2) sputter beam with high-current (>50 nA at 500 eV with a spatial resolution < 40 µm) for depth profiling of semiconductor samples and (3) a 30 kV high-resolution Bi nanoprobe with a spatial resolution < 50 nm. The instrument shall be able to operate with either the ToF analyser or the Orbitrap analyser or a combination of the two as described in the Nat. Methods paper. (4) a Ga focused ion beam with accelerating voltages of up to 30 kV, minimum bema diameter of 60nm and beam current > 25 nA. The OrbiSIMS shall be equipped for cryogenic analysis (sample holder temperature < -150 oC) and be compatible with and including Leica sample holders and allow the docking of a Leica VCT-500 cryo transfer vessel. It shall have two high-resolution TV cameras for direct sample observation and rapid location of the area of interest, as well as a photo box for high-resolution sample navigation. In addition to mass analysers, the instrument shall have a pulsed high-quality Everhart-Thornley secondary electron detector, located at grazing incidence to the sample, for primary ion induced secondary electron imaging and a self-adjusting charge compensation system using a pulsed, low energy electron flood gun. Samples shall be mounted using a rapid sample introduction system, with one sample holder for rear mounting of up to 18 samples with maximum dimensions of 10 mm x 10 mm x 8 mm, including mounting accessories, one sample holder for top mounting of multiple samples on an area of 100 mm x 80 mm with a maximum thickness of up to 20 mm, and one sample holder for mounting samples for cryogenic analysis.

II.2.11) Information about options

Options: No

II.2.13) Information about European Union funds

The procurement is related to a project and/or programme financed by European Union funds: No

Section IV: Procedure

IV.1) Description

IV.1.1) Type of procedure

Award of a contract without prior publication of a call for competition

Justification for selected award procedure:

The procurement falls outside the scope of application of the Directive

Explanation:

The OrbiSIMS concept was created at NPL and the first prototype instrument was built in a collaborative project with IONTOF and ThermoFisher Scientific. The instrument was subsequently commercialised by IONTOF and sold as the Hybrid SIMS. IONTOF are the only manufacturer of this type of instrument. A number of features of the OrbiSIMS instrument are protected by international patents. Unique features of the OrbiSIMS instrument include:

1. Imaging of biomolecules from tissue using a gas cluster ion beam with a spatial resolution of < 2 µm simultaneously with a mass resolving power of > 240,000 at m/z 200.

2. Depth resolution of < 10 nm of organic molecules in an organic multilayer reference sample simultaneously with a mass resolving power of > 240,000 at m/z 200.

3. Depth resolution of < 2 nm of ions in an inorganic semiconductor delta-layer reference sample simultaneously with a mass resolving power of > 240,000 at m/z 200.

4. Cryogenic imaging (see requirement 1) with a sample holder temperature of < -150 oC. Samples shall be mounted on Leica sample mounts. The instrument shall accept docking of a Leica VCT-500 cryo transfer vessel and have provision to receive samples into the instrument.

IV.1.8) Information about Government Procurement Agreement (GPA)

The procurement is covered by the Government Procurement Agreement: No

Section V: Award of contract/concession

V.2 Award of contract/concession

V.2.1) Date of conclusion of the contract/concession

23/01/2023

V.2.2) Information about tenders

The contract has been awarded to a group of economic operators: No

V.2.3) Name and address of the contractor

IONTOF GmbH

Heisenbergstr 15

Munster

48149

DE

NUTS: DE

The contractor is an SME: No

V.2.4) Information on value of the concession and main financing terms (excluding VAT) V.2.5) Information about subcontracting

The contract/concession is likely to be subcontracted

Section VI: Complementary information

VI.4) Procedures for review

VI.4.1) Review body

NPL Management Ltd

Hampton Road

Teddington

TW11 0LW

UK

VI.5) Date of dispatch of this notice

23/01/2023

Information added to the notice since publication.

Additional information added to the notice since it"s publication.

Commodity Categories

Commodity Categories

Delivery Locations

Delivery Locations

Alert Region Restrictions

The buyer has restricted the alert for this notice to suppliers based in the following regions.

Alert Region Restrictions

Источник закупки

Перейти

Импорт - Экспорт по стране Великобритания (Англия, Шотландия, Уэльс)